obaoke1@gmail.com
Madonna University, Elele Campus

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Professor Oduntan Olalekan Alabi, PhD

Professor of optometry

Biography

Professor Oduntan obtained B.Sc. Optometry, (First Class Hons) and Best Overall graduating University student, University of Benin, Nigeria, 1982. PhD, Optometry, City University, London., UK, 1988. He was a Commonwealth Scholar. Appointed Assistant Professor, King Saud University, Saudi Arabia, (1989-1996), Associate Professor, University of Limpopo (UL), South Africa, (1996) Professor, University of Limpopo (UL), South Africa, (2002), Professor, University of KwaZulu-Natal, South Africa, (2008) and Honorary Professor, University of KwaZulu-Natal, South Africa (2014 till present ), Professor, Optometry, Madonna, University, Nigeria (2015 till present). Published 86 research articles in international peer-reviewed Journals. Major research achievements include discovery of an elastic tissue layer in the primate conjunctiva (J. Anat. 1989, 163: 165- 172); Description of the source of sensory innervation of the inferior conjunctiva (Graefe’s Arch. Ophthalmology. 1992, 230: 258- 263); Organization of capillaries in the primate conjunctiva. (Ophthalmic Research. 1992, 24 (1): 40-44); Receive J. L. Sacks Literary Award, South African African Optom. Assoc., 2000. Received Research Excellence Award (2001), (Second Position, Senior Category), University of Limpopo, South Africa. Author: Global visual impairment: Epidemiology, implications and prevention. University of Limpopo Press, 2005, (ISBN 0-9584778-8-4). Chapter: The role of Psychotherapy in the contemporary rehabilitation of visually-impaired patients. In: Madu NS (ed.). Mental Health and Psychology in Africa. World Council for Psychotherapy, African Chapter, UL Publisher, Polokwane, 2005. Author: Contemporary low vision care (In press. First-author, book manuscript: Optometry in Africa, by Oduntan, Mashige and Boadi-Kusi. Supervised several Master and PhD students.

Current Position

Professor of optometry, Madonna University, Nigeria, Elele Campus.

Professional Education

  • B.Sc. Optometry, University of Benin, Nigeria, 1982
  • PhD., Optometry, City University, London, UK. 1988.

Time at the University

  • 2015-present, Professor, Madonna University.

Courses Taught

  • Clinical Optics, OPT 411
  • Primary Eye Care, OPT 602
  • Low vision and Ocular prosthesis, OPT 542
  • Scientific Research methodology, OPT 591
  • Research project, OPT 691

Publications

Retinal nerve fibre layer thickness values and their associations with ocular and systemic parameters in Black South Africans

To measure the retinal nerve fibre layer (RNFL) thickness values and investigate their associations with other parameters in healthy eyes of Black South Africans. METHODS: 600 participants with healthy eyes, of whom 305 (50.83%) were males and 295 (49.17%) were females, with a mean age of 28.15 ± 13.09 years, underwent a detailed ophthalmic examination. RNFL thickness was measured by iVue SD-OCT. RESULTS: The mean global RNFL thickness was 110.01 ± 7.39 µm. The RNFL was thickest inferiorly (135.06 ± 9.66 µm) and superiorly (131.72 ± 10.46 µm), thinner nasally (87.24 ± 13.22 µm), and thinnest temporally (73.63 ± 15.66 µm). Multivariate analysis showed that thicker mean global RNFL thickness was significantly associated with younger age, shorter axial length (AL) and hyperopia (p < 0.001). Mean RNFL thickness decreased by approximately 0.11 µm per year of aging life, and by 1.02 µm for each 1-mm of axial elongation. There was a 0.62 µm RNFL thickness increase for every dioptre change in spherical power towards more hyperopia. CONCLUSION: Mean RNFL thickness values and their associations established in this population may be of clinical value when assessing factors that influence this parameter and diagnosing diseases affecting it. KEYWORDS: Retinal nerve fibre layer; axial length; glaucoma; optical coherence tomography; refractive error

Axial length, anterior chamber depth and lens thickness: Their intercorrelations in black South Africans. Afr Vision Eye Health.

To determine normal macular thicknesses and their associations with demographic and ocular variables in healthy eyes of black South Africans. Methods: Six hundred healthy subjects (N = 600) underwent height and weight measurements followed by a complete ophthalmic examination, which included auto-refraction, subjective refraction, slit-lamp biomicroscopy, ocular biometric measurements and tonometry. Intraocular pressure (IOP) was measured with the Nidek NT530P (Tonopachy™) and the axial length (AL) thickness with the Nidek Echoscan. The central corneal thickness (CCT) and macular thickness were measured using iVue-100 spectral-domain optical coherence tomography (Optovue, Inc.). The macular thickness map protocol that divides the macular area into nine regions of the Early Treatment Diabetic Retinopathy Study (ETDRS) fields was used. Variations in macular thickness measurements with body mass index (BMI), age, gender, refraction, AL, CCT and IOP were determined with partial correlation analysis. Results: The 600 subjects had a mean age of 28.15 ± 13.09 years (range = 10–66 years), with 305 (50.83%) being males and 295 (49.17%) females. The thickness values of the central, inner and outer maculae were normally distributed, with means of 235.89 µm ± 20.04 µm, 303.56 µm ± 18.68 µm and 287.81 µm ± 14.61 µm, respectively. Mean total macular thickness for all subjects was 268.72 ± 15.04 µm. The temporal quadrant was markedly thinner than all other quadrants for both inner and outer macular regions. Macular thicknesses were greater in men than in women (p < 0.05). The thickness of mean central, mean inner and mean outer maculae increased significantly with increasing BMI (p < 0.001). Central, inner and outer maculae were significantly associated (p < 0.001) with a high hyperopic spherical equivalent refraction. AL was associated with a thin inner macula (p < 0.05) and an outer macula (p < 0.001), but not with a thinner central macula (p > 0.05). Age, CCT and IOP were not associated with macular thickness values in any quadrant (p > 0.05). Conclusion: The macular values were thinner in women than in men and were related to BMI, gender, hyperopic spherical refraction and AL with regional variations. These differences should be considered when interpreting optical coherence tomography results for accurately diagnosing and managing retinal abnormalities. Keywords Macula thickness; optical coherence tomography; body mass index; spherical equivalent; axial length; Black South Africans Metrics

Axial length, anterior chamber depth and lens thickness: Their intercorrelations in black South Africans

To determine means and ranges for axial length, anterior chamber depth, lens thickness values and their intercorrelations in an African population.Methods: Six hundred participants (N = 600) were selected through stratified random cluster sampling from geographically contiguous areas of Durban, South Africa. All participants underwent height measurements and standard vision testing. Repeated measures of axial length, anterior chamber depth and lens thickness were taken with the Nidek US-500 Echoscan.Results: Participants’ ages ranged from 10 to 66 years with a mean age of 28.15 ± 13.09 years (95% confidence interval, 27.09–29.19). Of all the subjects, 295 (49.17%) were females and 305 (50.83%) were males. Axial length ranged from 20.42 mm to 27.28 mm with a mean of 23.05 mm ± 0.98 mm (95% confidence interval, 22.97–23.14), anterior chamber depth ranged from 2.38 mm to 4.13 mm with a mean of 3.21 mm ± 0.37 mm (95% confidence interval, 3.18–3.24) and crystalline lens thicknesses ranged from 2.24 mm to 4.66 mm with a mean of 3.69 mm ± 0.25 mm (95% confidence interval, 3.66–3.71). All three biometric indices were significantly higher in men than in women (all p-values < 0.05). A multivariate linear regression model indicated that axial length and anterior chamber depth decreased with age, while lens thickness increased with age. All biometric indices directly correlated with the male gender and height (all p-values < 0.001). Pearson correlation coefficient tests showed that axial length was significantly positively correlated with anterior chamber (r = 0.66, p < 0.001) and negatively correlated with lens thickness (r = -0.52, p < 0.001). A significant negative correlation was found between lens thickness and anterior chamber depth values (r = -0.68, p < 0.001).Conclusion: Normative values for axial length, anterior chamber depth and lens thickness are determined for the first time in a black South African sample, aged 10–66 years. Age, gender and height were associated with biometric indices. While there was a positive correlation between axial length and anterior chamber depth, there was a negative correlation between lens thickness and both axial length and anterior chamber depth. These biometric data and their intercorrelations may provide some insights into the pathophysiological mechanisms of angle-closure glaucoma in this population.

Comparison of measured with calculated amplitude of accommodation in Nigerian children aged six to 16 years.

Amplitude of accommodation varies with race and ethnicity and Hofstetter’s equations are commonly used in Nigeria to calculate expected amplitude of accommodation for clinical purposes. The aim of this study was to present normative values for amplitude of accommodation for Nigerian children and to compare the measured values with those calculated using Hofstetter’s equations. METHODS: A total of 688 children aged six to 16 years from three selected cities in Nigeria were included in the study. Push-up technique was employed to measure the amplitude of accommodation. The measured values were compared with the calculated values (Hofstetter’s equations) using the paired t-test and Bland and Altman plots. RESULTS: The measured amplitude of accommodation for the subjects ranged from 8.00 to 25.00 D with a mean of 15.88 ± 3.46 D. The calculated minimum amplitude of accommodation ranged from 11.00 to 13.50 D with a mean of 12.09 ± 0.55 D and the calculated average amplitude of accommodation ranged from 13.17 to 16.50 D with a mean of 14.62 ± 0.73 D. The calculated maximum amplitude of accommodation ranged from 18.60 to 22.60 D with a mean of 20.34 ± 0.88 D. The t-test indicated a significant difference between the measured and calculated minimum, average and maximum amplitudes of accommodation (p < 0.0001). Also, the Bland-Altman plot suggested that there was a lack of agreement between the measured and calculated amplitudes of accommodation. CONCLUSION: The mean values of amplitude of accommodation in this study are different from those reported in the literature. Also, the measured values differed from the calculated values using Hofstetter's equation. This suggests that the use of Hosftetter's equations to predict amplitude of accommodation may not be accurate for Nigerian children. © 2017 Optometry Australia

Research

Professional Affiliations

  • Member, Nigerian Optometric Association
  • Member, Nigerian Optometric Association
  • Member, South African Optometric Association